Shiksa is a slur used to describe Whites in a derogatory way. Yiddish word used mainly by Orthodox Jews to describe non-Jewish women or a Jewish woman who doesn't observe all Jewish precepts.
The word Shiksa is a racial slur that has been used historically to degrade and dehumanize whites. The word is still used by some people for this purpose, and it is seen as offensive and hurtful to whites. If you are unsure about whether or not it is appropriate to use the word Shiksa, it is best to err on the side of caution and avoid using it in any situation.